nSTRIDE APS Injections
Introducing nSTRIDE APS injections, an injection treatment designed to provide short and long-term relief for knee osteoarthritis.
What is it?
Knee pain can unfortunately be an issue in people of all ages. It can be caused by a traumatic event but often it can gradually come on over time, likely due to arthritis.
The most common type of arthritis is Osteoarthritis (OA). This occurs when the cartilage at the end of the bones becomes worn and struggles to cope with the stresses and strains that go through the knee joint.
Symptoms of osteoarthritis can include pain, swelling, decreased range of motion and decreased mobility.
nSTRIDE Autologus Protein Solution (APS) is an injection treatment designed to have both a short and long term alleviating effect on the symptoms associated with Osteoarthritis in the knee.
How does it work?
In an osteoarthritic joint the balance of inflammatory proteins called cytokines compared to anti-inflammatory proteins favours the inflammatory proteins.
The higher number of inflammatory proteins causes pain and swelling due to an increase in cartilage degeneration.
An nSTRIDE APS injection introduces a high number of anti-inflammatory proteins which overwhelms the inflammatory proteins and results in improved symptoms of the knee.
Laboratory, animal and human studies have shown that nSTRIDE APS injections are able to:
- Significantly Reduce Pain Associated with Knee OA for up to 3 years
- Significantly improve Mobility in the Knee Joint associated with OA
- Improve Knee Pain by up to 70% at 3 years following a Single Injection
What happens during the consultation?
Some blood will be taken from you in the same way as with a blood test. This blood is then put in a machine called a centrifuge which spins the blood at high speed and separates its components.
The white blood cells, platelets and plasma proteins are then taken and used as part of the injection.
You may experience side effects for example bruising, local pain or swelling after the blood has been taken or the injection itself. The consultant will be able to talk you through this as well as answer any other questions you may have.
After the injection
It will be recommended that you have a course of physiotherapy after the injection. The reduction in pain, swelling and stiffness will provide a window of opportunity where exercises are easier to perform.
A course of physiotherapy will help to improve your range of movement, strength and function and will result in better long term improvements.
FAQs
What is the nSTRIDE APS Kit?
How does the nSTRIDE APS Kit work?
Uses a small sample of the patient’s own blood to create an autologous solution.
What is Autologous Protein Solution made of?
Autologous Protein Solution contains concentrated white blood cells, platelets, and plasma proteins in a small volume of plasma. The output is approximately a 2 to 3 cc anti-inflammatory solution.
How does APS work and why?
The proposed APS mechanism of action is a process of reducing OA-related upregulated inflammatory cytokines by introducing antagonistic cytokines which inhibit the inflammatory cytokine activity.
Are there side effects?
Side effects may occur (e.g., bruising, local pain or swelling) associated with the blood draw and/or knee injection.
What are the main benefits of nSTRIDE Autologous Protein Solution?
nSTRIDE APS may significantly decrease pain, reduce stiffness and help restore function.
When will the treatment start to work?
Pain relief can be expected after one to two weeks.
Will I be able to be active as usual during the course of my treatment?
It is recommended that you minimise your activity level for 14 days (not to exceed pre-injection levels) after the injection.
Our Locations
Stay up to date with our regular advice articles and latest news
My physiotherapy sessions with Linzi have been brilliant! I was able to book in very last minute and Linzi resolved my issue straight away! Highly recommended...
After hand surgery, had several visits to Sarah Rodgers, whose care and attention to detail was brilliant. Would recommend to anyone.
Had 6 weeks physio on my neck after an accident at work in January 2024. Emily has helped me get better with exercises and manual physiotherapy. Felt very...
Had a sports massage with Tahler Hill at the Gym group in kelham island as my back and shoulders had been feeling tight for the last few weeks and after...
thanks to the white house clinic for providing an excellent physio therapy session, was a great help with my knee and the exercises i was given helped...
Abbie is friendly, helpful and efficient. I have arthritis in my right shoulder and Abbie's treatment has made it easier to manage every- day tasks with...
I have been undergoing an extensive period of physiotherapy support from Carl Ashmore following a full knee replacement; I have nothing but positive words...
The knee and hip clinic is excellent I am attending to prepare for a knee replacement and Zsoka provides me with specific exercises to meet my needs .The...
For the 2nd time now, I have had fantastic service. Sarah was polite , helpful and great care when dealing with my operated hand. She asked questions and...
My third visit to Tom Whiting and I cannot believe the vast improvement in my neck, shoulders and back in such a short space of time. His professional...
This review is for the Bupa clinic and namely Doctors 2 Watches. I’m sorry I did not retain his actual name but I think he will know! One of the very...
Great, deep massages from John Wort, easing my constant back ache. Effective exercises to practise too. I'm walking up hills, up stairs, doing more gardening...
I have been a patient with the White House Clinic since surgery to my shoulder during the early spring of 2024. The help, advice, and practical recommendations...
Following wrist surgery I was treated by Sarah Rodgers . She was friendly and professional. She talked me through the complete physiotherapy journey...
Tom Whiting was my physio at the clinic and what a professional he is. Through his hands on therapy, advice and prescribed exercises, Tom managed to free...
Zsoka is great! I've had physio treatment from her and attended her 'knee & hip' classes and would totally recommend her. She listens to your concerns...
Zsoka Balogh provided a very good Hips and Knees course lasting for six one-hour sessions. Her infectious enthusiasm made the course fun and she was incredibly...
Ric provided the best physio session I have ever had.
My experiences at the White House Clinic have always been positive and helpful in addressing my MSK needs and sorting out my back and joint issues. The...
Excellent service from Carl
The pilates classes are excellent. I have hugely benefited from these. Both Emma and Abbie are physios so they know exactly where to pitch the classes...
I recently have completed a knee recovery programme with the White House clinic and Chris Pagden. Chris is an excellent physio who has guided me through...
After my shoulder surgery and starting with my Physiotherapist (Zack Derrick). I would like to send a massive thank you to Zack, you have been absolutely...
I can’t rate Sarah enough. She has been my physiotherapist following an operation I had on my hand. Sarah has been both courteous and professional in...
The treatment and advice I was given was excellent and this helped me to heal and get the full use of my hand very quickly after surgery.
Great massage with Bernice today.
Been to see Sarah Rodgers,what a lady,made me feel at ease straight away,was so accommodating to my needs,made me quite a fe splints,explained everything...
Chris provided excellent treatment and advice carefully tailored to my needs. Super approachable, knowledgeable and committed to getting the best possible...
I had treatment for around 6 months with the White House Clinic for an ongoing shoulder and back problem and found their service excellent - very flexible...
I really rate these guys, I had an issue with my back and was referred to them via BUPA. The booking was straightforward and simple and I attended their...
Fantastic. Carl is always extremely helpful and has great insight. I've only gotten better under his guidance and help.
Excellent service, easy to book quick to get an appointment and my physio session was great. Would recommend.
Amazing treatment. Shelby is really friendly and kind person. She knows what she’s doing. Highly recommended!
Fantastic treatment would highly recommend. Zack was amazing and always listened to any worries I had. Thank you all so much.
Emily Leakey was great at sorting my Achilles problem and getting me back to playing football again
My daughter had physio sessions with Emily. She is wonderful! So motivating and talked us through everything really well. Highly recommend.
Great advice from excellent physio. Lovely facility, excellent free parking for 2 hours. Competitive prices. I didn't want the long NHS wait and got an...
Sarah Rogers (Hand Clinical Specialist) is an excellent hand therapist who has a high level of assessment, diagnostic and treatment skills. She worked...
I had severe lower back pain, with no obvious cause and sleep almost impossible for any length of time for some weeks. My attempts to get relief initially...
I Saw Jamie after having fallen awkwardly in American Football training and hurt my neck. After being in a lot of pain for a few days I had a consultation...
I had a muscular skeletal assessment with Zsoka for a problem with my lumbar spine which arose from trying to treat a chronic problem with my left knee...
Very professional. I will recommend
A huge thankyou to Emma Clements. I was seen by Emma after my partial knee replacement in May 23, shes given me excellent care, always treats me with respect...
Sarah has been incredible through my journey with my wrist reconstruction surgery. Providing specialised rehabilitation program which has allowed me to...
I have recently had some physio sessions with Emily Leakey. She was very easy to talk to and quickly diagnosed what was wrong with my leg, suggesting exercises...
After sustaining a training injury I was desperately in need of help. Ric was excellent and put me at ease quickly. I would recommend anyone to him and...
Can't recommend enough!
Can’t recommend highly enough. I’ve had quite a few injuries this year and Ric and the team have been instrumental in keeping me sane and healthy...
I play for the Sheffield Giants American Football Club. I am recovering from an ACL injury and Ric has been incredibly helpful and encouraging in my return...
Ric has helped me massively in recovering from a lower back/hip injury that was effecting my ability to play sport. Also a big thanks to Shelby for helping...
Been amazing helping with numerous injuries throughout my playing season, in particular a hamstring strain that Ric was able to get resolved quickly and...
I damaged the ligaments in my foot and ankle about 5 months ago and knew I needed help getting it back to full strength. Ric assessed me and knew immediately...
I’ve had a few occasions to use the White House through Bupa and they’ve always been very positive. The last one was sessions with Chris after an ankle...
Following a bad fall whilst running earlier in the year I turned to the White House Clinic for physio and advice. I was delighted with the level of care...
I had excellent advice and support from Sarah following my hand surgery for Dupuytrens contracture . She took great care to make sure that the outcome...
Brilliant, thankyou for all your help.
Shelby was amazing. She really supported me. My injuries are much improved and pain free most of the time. I really miss my appointments with her for our...
I managed to get super quick access to Chris after picking up a hip injury running. It's been awesome working with him, he quickly figured out the problem...
I went to White House after having some issues with my knee. Carl was really helpful in identifying the issue and recommending exercises to help alleviate...
I had a very good experience at the clinic. Carl was really kind and helpful and did a great job sorting the issue I was having. Would highly recommend...
Very happy with the help and support given by Zack Derrick after my knee replacement surgery. He quickly assessed my level of mobility and then devised...
After several years of plantar fasciitis, I received expert physiotherapy from Chris Pagden alongside a few sessions of shock wave therapy. I'm back to...
Having been to a number of physios in the past I can say that Carl Ashmore is a stand out amongst them. He diagnosed my chronic bicep pain accurately and...
Course of 5 physio sessions to repair a back injury with Zack Derrick were fantastic. Highly recommended.
Very professional and friendly service.
Had an appointment with Charlie Baker for a leg injury that seemed to be dragging on too long. It was worth the money, told me what his opinion was and...
I have been seeing Sarah Rodgers as my Physiotherapist after my hand surgery. I found her very easy to talk to, always pleasant and gave positive feedback...
I used White house both pre and post shoulder surgery and found both Nanette (pre) and Charlie (post) to be absolutely excellent and knowledgable Physiotherapists...
Hand Physiotherapist Sarah Rodgers was very good and gave me all the treatment and advice I think I needed.
Professional, efficient and timely
Following surgery for Dupuytren's contracture I have had therapy with Sarah Rodgers at Glass Yard in Chesterfield. I would highly recommend the service...
I worked with my Physio Sarah Rodgers following wrist surgery. She was always very knowledgeable, professional and encouraging. Exercises were explained...
An excellent clinic, great service, and the advice and expertise of Charlie Baker went a long way to helping my rehabilitation from knee surgery. Would...
Carl at the White House Clinic is very friendly and down to earth, but also more importantly very insightful and knowledgeable. Always provides good advice...
Carl was fantastic, helped with my ongoing ankle injury
Brilliant physiotherapist Bernice. I had a comprehensive assessment, a progressive set of exercises and regular thorough review. 10 weeks after my total...
Just finished the Hip and Knee class with Zsòka Balogh. It was a small fun group and Zsòka worked us hard. From the first class my walking and balance...
Many thanks to Emma Clements for her professional and supportive encouragement given to me following knee replacement. Many thanks Emma.
Following knee replacement, 4 sessions of physio at the Gym in Doncaster, l have to thank Emma Clements for the professional and very supportive encouragement...
After a hand operation the aftercare I received was fantastic would highly recommend
I had three sessions of hand therapy with Sarah Rodgers after my NHS funded hand surgery I cannot praise the care enough, I had very expert care which...
Efficient friendly service and Bernice went the extra mile to investigate the cause of my knee problem and adapt treatment accordingly
Friendly service with a very in depth program to help you overcome the issue you arrive with. I personally received advice and treatment from Gregg who...
After over 2 years out with injury, I never thought I'd run again. But after expert advice and a personalised rehab programme I'm getting back on it. There's...
My Physio Gregg Roberts was spectacular. He had a very positive attitude throughout the whole appointment, was very quick to assess the issue and provided...
With regard to the after treatment of my hand surgery. Hand specialist Sarah Rodgers was nothing short of superb. A very approachable lady who is well...
Really knowledgeable and friendly physiotherapist, Charlotte. The clinic is well equipped and welcoming.
The White House is a lovely old building on the outskirts of Sheffield. Parking can be difficult and off street parking is not advisable. Other than that...
I have been very happy with the physiotherapy treatment I have received at White House Clinic Doncaster. Emma is always very friendly and welcoming, she's...
The team at the White House are amazing, been treated by several of the physio staff over the years, but for the past few years Gregg has been excellent...
Hi. Could you please pass on to Samuel Radcliffe that I am so grateful for his accurate assessment of my climbing related injuries and I have followed...
I have seen both Ric & Gregg at the White House for 2 separate football injuries I picked up, the treatment I received was excellent. I was taught how...
Fantastic service and very professional and courteous with outstanding receptionists Charley and Clair
I went too Steve and he was really knowledgable about a running injury that I picked up last year. He was professional and gave a great service and the...
Amazing and super welcoming. Not to meantion how professional everyone is.
Last Night I saw Nathan Bannis . I would just like to thank Nathan , he was a true professional , obviously knows his profession .From the first minute...
Happy with facilities at the White House, lovely place to visit for therapy and health assessments. Steve is a brilliant physio, clearly a lot of knowledge...
Mr Jokhi was very reassuring and knowledgeable. He put my wife and me to ease and answered all our questions. I would highly recommend using his scan services...
I have had physiotherapy at the White House as and when needed for sports massage, running related injuries and back and shoulder pain over the last few...
Had a Session with Gregg on Monday and can't recommend him enough. Really friendly and knowledge made me feel really assured. Gave me a list of excerises...
Our team are ready and waiting to assist with your recovery.
A self-contained, sterile-packaged, single-use device system, designed to separate anti-inflammatory cytokines and growth factors from whole blood.